Sage at AACR
Enabling radically collaborative cancer research.
Helping cancer research teams accelerate their work and extend their impact.
Enabling discovery and empowering communities through the support of sponsored cancer research programs and global partnerships
Cancer program portfolio
Where cancer researchers collaborate across systems — from real-world data to cell atlases to open discovery.
Cancer Complexity Knowledge Portal (CCKP), designed and maintained by Sage Bionetworks, hosts an interconnected ecosystem of data, publications, software tools, and educational resources generated through NIH funded projects investigating various aspects of Cancer.
Six different research consortia working on various themes ranging from metastasis to tumor-immune interaction, to computational models of disease mechanisms are represented and connected through this Portal. The Portal serves experimental biologists, physician scientists, and computational researchers looking to find and re-use previously generated data and software tools by the cancer research community and share newly generated resources to move the current research in the domain forward.
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AACR Project GENIE® is an international clinico-genomic data sharing initiative led and funded by the American Association for Cancer Research (AACR), pooling real-world cancer genomic and clinical data to advance precision medicine.
Sage Bionetworks has served as a strategic partner with AACR for over a decade as a core member of the Project GENIE Coordinating Center, supporting large-scale data harmonization, governance, and reuse.
- Cancer Centers19
- Samples250K+
- Patients211,527
- Public Release18.0
HTAN is a National Cancer Institute (NCI)-funded Cancer Moonshot initiative to construct 3-dimensional atlases of the dynamic cellular, morphological, and molecular features of human cancers as they evolve from precancerous lesions to advanced disease.
The HTAN Data Coordinating Center, led in partnership by Sage Bionetworks, ISB, MSKCC, and DFCI, standardizes, integrates, and distributes multimodal tumor data to ensure long-term reuse, interoperability, and impact.
- Atlases14
- Cases2372
- Multimodal data334 TB
- Organs20
- Biospecimens11,000+
Cancer Challenges are open, community-driven competitions that bring together global researchers to benchmark methods, accelerate discovery, and advance cancer research through transparent evaluation.
Hosted on Synapse and supported by Sage Bionetworks, these challenges enable reproducible science by providing shared datasets, evaluation metrics, and open leaderboards across critical cancer domains.
Explore Cancer ChallengesHow We Work
We support infrastructure, engineering, and governance across leading cancer research programs. Learn how we build platforms and partnerships that accelerate open, reproducible science.
Community Organization
We support a collaborative cancer research community through shared data, resources and tools, as well as opportunities to learn and work together. These community interactions drive new collaborations, transdisciplinary science, and faster and more novel scientific discoveries.
Data Infrastructure
We design and maintain research platforms, data pipelines, and analysis tools that enable scientists to explore complex datasets, reproduce results, and collaborate efficiently at scale.
Data Governance
We establish governance frameworks that balance openness with responsibility—supporting consent, privacy, access controls, and compliance so data can be shared ethically and sustainably.